Each player draws 7 caption cards. A judge, who alternates among the players, selects the image card to be used in that round. The image is shown to the players and placed on the provided stand. Players must choose the caption that best fits the image from the 7 available cards. Once all caption cards have been submitted, the judge can take them from the table, shuffle them, and read them aloud one by one. The funniest caption wins the round, and the player who suggested it keeps the image card as a trophy (1 image card = 1 point). The player who collects the most image cards wins. The NSFW expansion adds 90 caption cards to What Do You Meme? - only in Italian.