Compared to the Radeon 5450, the Radeon 6450 shows significant improvement. The most notable update is that the Radeon 6450 features 160 stream processors, which is twice as many as the previous generation Radeon 5450, resulting in stronger performance. Additionally, the prices of both cards are quite similar, making the Radeon 6450 a better option in terms of cost performance.

As an entry-level graphics card, the Radeon 6450 has very low power consumption, with a maximum power draw of only 27W. The heat output of the graphics card is also well managed, ensuring stable operation even when using a passive cooler.