As part of a special police unit, it's up to you to fight against mysterious alien creatures that have invaded the world. In the Ark, a multicultural city in the near future, disaster strikes when gates to another dimension suddenly appear. Dangerous creatures appear, attacking the people and infesting the land, and the normal police forces are unable to stand against them. To defend against these threats, a brand new special unit called Neuron is formed. Choose between two playable characters - one male and one female - on your adventure. The character you don't choose will also appear as your younger twin and as a member of Neuron. To defend itself against the creatures, humanity has developed a special weapon: the Legion. The Legion acts as your partner and helps you with your investigations. However, the Legion only shows its true capabilities in battle.

Employ employees of the Legion and use all possible combat styles to fight your enemies. You can both attack the same enemy at the same time, target different enemies or send your Legion on the offensive while you support them with items. Use this synergetic action system to fight and explore together.

Takahisa Taura, who is making his directorial debut and is known for his work as game designer on NieR:Automata, is responsible for the concept and planning of Astral Chain. Hideki Kamiya, the creator of the Bayonetta series, is in charge of supervision. The character design is by manga artist Masakazu Katsura, the creator of Zetman and Video Girl Ai.