Yes, it is compatible with the CPU

This is the answer from https://chat.openai.com/chat;

The Ryzen 7 5800X processor uses the AM4 socket, which is also used by the ASUS ROG Strix B450-F Gaming motherboard. However, to use the Ryzen 7 5800X on the ASUS ROG Strix B450-F Gaming motherboard, you will need to make sure that the BIOS version of the motherboard is updated to the latest version that supports the Ryzen 5000 series processors.

Some B450 motherboards may not have the necessary BIOS update to support Ryzen 5000 series processors out of the box, so you may need to update the BIOS manually before installing the CPU. You can check the ASUS website to see if the BIOS for your motherboard supports the Ryzen 5000 series processors and download the latest version if needed.

In summary, the Ryzen 7 5800X is compatible with the ASUS ROG Strix B450-F Gaming motherboard, but you will need to make sure that the motherboard has the latest BIOS version that supports the Ryzen 5000 series processors.

A really great source for this sort of question; Happy Building, David